Mono-chloro-substituted m-dinitrobenzene compound as cathode materials magnesium battery

The performance of mono-chloro-substituted m-dinitrobenzene compounds in magnesium battery is reported here. While the operating voltage is improved, the current efficiency is lowered by the chloro-substituents. The influence is explained taking into account inductive and mesomeric effects of the substituent

Analyzing Variability in Coleus forskohlii Briq. Using RAPD Markers

Coleus forskohlii Briq. is an indigenous medicinal plant with high traditional use in India. Genetic analysis of 37 diverse C. forskohlii genotypes was performed using 25 RAPD primers, which yielded 117 bands, of which 60 (51.28%) were polymorphic providing an average of 3.75 bands per primer. There were no genotype-specific products. The number of bands per primer varied from 1 (OPZ 8&16) to 7 (OPZ 11). Similarity matrix was constructed using Jaccard's Coefficient and the data matrix of coefficient of similarity was subjected to cluster analysis using unweighted pair group methodology with arithmetic average (UPGMA). Cluster analysis resulted in grouping of 37 genotypes into two major clusters. The results indicated that RAPD could be used for genetic diversity analysis in C. forskohlii using higher number of primers as it is reliable, easy, rapid and cost-effective

Gabapentin for chronic pelvic pain in women (GaPP2): a multicentre, randomised, double-blind, placebo-controlled trial

Background: Chronic pelvic pain affects 2–24% of women worldwide and evidence for medical treatments is scarce. Gabapentin is effective in treating some chronic pain conditions. We aimed to measure the efficacy and safety of gabapentin in women with chronic pelvic pain and no obvious pelvic pathology. Methods: We performed a multicentre, randomised, double-blind, placebo-controlled randomised trial in 39 UK hospital centres. Eligible participants were women with chronic pelvic pain (with or without dysmenorrhoea or dyspareunia) of at least 3 months duration. Inclusion criteria were 18–50 years of age, use or willingness to use contraception to avoid pregnancy, and no obvious pelvic pathology at laparoscopy, which must have taken place at least 2 weeks before consent but less than 36 months previously. Participants were randomly assigned in a 1:1 ratio to receive gabapentin (titrated to a maximum dose of 2700 mg daily) or matching placebo for 16 weeks. The online randomisation system minimised allocations by presence or absence of dysmenorrhoea, psychological distress, current use of hormonal contraceptives, and hospital centre. The appearance, route, and administration of the assigned intervention were identical in both groups. Patients, clinicians, and research staff were unaware of the trial group assignments throughout the trial. Participants were unmasked once they had provided all outcome data at week 16–17, or sooner if a serious adverse event requiring knowledge of the study drug occurred. The dual primary outcome measures were worst and average pain scores assessed separately on a numerical rating scale in weeks 13–16 after randomisation, in the intention-to-treat population. Self-reported adverse events were assessed according to intention-to-treat principles. This trial is registered with the ISRCTN registry, ISCRTN77451762. Findings: Participants were screened between Nov 30, 2015, and March 6, 2019, and 306 were randomly assigned (153 to gabapentin and 153 to placebo). There were no significant between-group differences in both worst and average numerical rating scale (NRS) pain scores at 13–16 weeks after randomisation. The mean worst NRS pain score was 7·1 (standard deviation [SD] 2·6) in the gabapentin group and 7·4 (SD 2·2) in the placebo group. Mean change from baseline was −1·4 (SD 2·3) in the gabapentin group and −1·2 (SD 2·1) in the placebo group (adjusted mean difference −0·20 [97·5% CI −0·81 to 0·42]; p=0·47). The mean average NRS pain score was 4·3 (SD 2·3) in the gabapentin group and 4·5 (SD 2·2) in the placebo group. Mean change from baseline was −1·1 (SD 2·0) in the gabapentin group and −0·9 (SD 1·8) in the placebo group (adjusted mean difference −0·18 [97·5% CI −0·71 to 0·35]; p=0·45). More women had a serious adverse event in the gabapentin group than in the placebo group (10 [7%] of 153 in the gabapentin group compared with 3 [2%] of 153 in the placebo group; p=0·04). Dizziness, drowsiness, and visual disturbances were more common in the gabapentin group. Interpretation: This study was adequately powered, but treatment with gabapentin did not result in significantly lower pain scores in women with chronic pelvic pain, and was associated with higher rates of side-effects than placebo. Given the increasing reports of abuse and evidence of potential harms associated with gabapentin use, it is important that clinicians consider alternative treatment options to off-label gabapentin for the management of chronic pelvic pain and no obvious pelvic pathology. Funding: National Institute for Health Research

Scientometric analysis of Spice research publications in India from SCOPUS database during 2010- 2019

This paper presents the scientometric analysis of Spice research publications in India from SCOPUS database during 2010 - 2019 with 3120 research publications. During the Study period, maximum of 400(12.82%) research publications are contributed in the year 2018 and 2019, average research publication per year is 312 and CAGR is 8.62. Relative growth rate is 0.92 in the year 2011 and 0.14 in the year 2019, at the same time doubling time is 0.75 in the year 2011 and 5.05 in the year 2019. Out of 3120 research publications, 179(5.74%) publications are contributed by single author’s publications and remaining 2941(94.26%) research publications are multi authors publications. The average degree of collaboration is 0.94. From this study, maximum of 91 (2.92%) research publications are contributed by Pandey, N, maximum of 38(1.22%) research publications are contributed by Analog Integrated Circuits and Signal Processing and maximum of 113(3.62%) publications are produced by Delhi Technological University. Maximum number of 48(1.54%) publications are funded by University Grants Commission. Bradford’s Law of Scattering study identified from Zone 1, 40(5.43%) journals were most prolific with 624(32.91%) research publications. The Collaborating countries in India, maximum of 119(3.81%) publications are contributions by United States and Indian authors are collaborated 62 countries with 480 research publications. Time series analysis study found that Spice research publications in Indian in the year 2025 is around are equal to 520 publications and the year 2030 is around are equal to 627 publications and this study confirmed Spice research publications in India is increasing trend

Scientometric analysis of pollution control research publications in Indian from SCOPUS database between 2007 and 2018

This paper aims to analyze the pollution control research publications by the Indian contributions from the scopus online database between 2007 and 2018 with 33084 research publications. Out of that, 1997 publications are contributed by India. This study examine the year wise growth of research publications, relative growth rate and doubling time, bibliographic form of publications, top 10 country wise contributions and authorship pattern. During the study period, maximum of 226(0.68%) publications are contributed in the year 2018. Activity index ranges between 79.89 and 121.86 during the study period. The relative growth rate is found that, 0.61 to 0.12 between 2007 and 2018. On the same time doubling time values are 1.14 to 5.77. During the study maximum of 1441 (72.16%) publications is article. 607 Indian authors research publications are collaborated by 69 other countries. Maximum of 112(5.61%) publications are collaborated by United States. The average degree of collaboration is 0.92, average collaborative coefficient is 0.61 and average collaborative index is 0.30. During the study period it is identified that, CAI for single, two and three authorship are decreasing trend

A Discrete Time Geometric Queue Attached to an Inventory under a (0, Q) Policy

This paper describes how a threshold policy, or TP = [(0, Q), 1]-based inventory management, economically offers customers a single product with a discrete time geometric queue attached to a Geo/Geo/1 service base. The order for Q units starts when inventory I(t) at time ’t’ drops to the level ’0’, and the length of the queueing process X(t) is at least one. We focus on the process Z(t) = (X(t), I(t)), t  [0, ?). We then analyse the steady state probabilities and then provides a numerical study for graphing the economic order quantity

Scientometric analysis of pollution control research publications in Indian from SCOPUS database between 2007 and 2018

This paper aims to analyze the pollution control research publications by the Indian contributions from the scopus online database between 2007 and 2018 with 33084 research publications. Out of that, 1997 publications are contributed by India. This study examine the year wise growth of research publications, relative growth rate and doubling time, bibliographic form of publications, top 10 country wise contributions and authorship pattern. During the study period, maximum of 226(0.68%) publications are contributed in the year 2018. Activity index ranges between 79.89 and 121.86 during the study period. The relative growth rate is found that, 0.61 to 0.12 between 2007 and 2018. On the same time doubling time values are 1.14 to 5.77. During the study maximum of 1441 (72.16%) publications is article. 607 Indian authors research publications are collaborated by 69 other countries. Maximum of 112(5.61%) publications are collaborated by United States. The average degree of collaboration is 0.92, average collaborative coefficient is 0.61 and average collaborative index is 0.30. During the study period it is identified that, CAI for single, two and three authorship are decreasing trend